Feasibility of circumferential pulmonary vein isolation using a novel endoscopic ablation system.

نویسندگان

  • Boris Schmidt
  • Andreas Metzner
  • Kyoung Ryul Julian Chun
  • Dionysios Leftheriotis
  • Yasuhiro Yoshiga
  • Alexander Fuernkranz
  • Kars Neven
  • Roland Richard Tilz
  • Erik Wissner
  • Feifan Ouyang
  • Karl-Heinz Kuck
چکیده

BACKGROUND Pulmonary vein isolation (PVI) is an established treatment option for patients with drug refractory paroxysmal atrial fibrillation. A novel compliant endoscopic ablation system housing a 980-nm-diode laser allows for discrete point-by-point ablation enabling a true circumferential ablation line design. We sought to determine the feasibility and safety of a circumferential ablation using endoscopic ablation system. METHODS AND RESULTS Thirty patients (17 female; mean age, 58±9 years) with a median paroxysmal atrial fibrillation history of 3 years (range, 1 to 17 years) were treated. PVI was achieved in 114 of 116 (98%) PVs (4 left common PVs), thereby achieving simultaneous PVI for separate ipsilateral PVs in 19 of 26 (73%) left PVs and 6 of 30 (20%) right PVs. The total procedure time was 250±62 minutes. Procedure time decreased from 310±59 to 220±37 minutes (P=0.0001) between the first 10 and the last 20 cases. Mean fluoroscopy time was 30±18 minutes. Twenty-seven patients underwent postoperative endoscopy showing no or minimal thermal lesions in the esophagus in 21 (78%) and 2 (7%), respectively. In 4 (15%) patients, an esophageal ulceration was found that healed without sequelae. One pericardial tamponade and 1 right-sided phrenic nerve palsy occurred. During a median follow-up of 168 days (113 to 203 days; q1-q3), 24 of 30 patients (80%) remained free of atrial fibrillation recurrence. CONCLUSIONS Circumferential PVI using the novel compliant endoscopic ablation system was feasible in the majority of left PVs and minority of right PVs accompanied by a complication rate comparable to established approaches. To minimize the risk for thermal esophageal injury temperature monitoring is recommended.

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عنوان ژورنال:
  • Circulation. Arrhythmia and electrophysiology

دوره 3 5  شماره 

صفحات  -

تاریخ انتشار 2010